Calcifediol Monohydrate

Other Name: 25-hydroxy Vitamin D3 monohydrate
CAS NO.: 63283-36-3
Molecular Formula: C27H46O3
Molecular Weight: 418.66
Appearance: White to Light Yellow Powder

Benefits
1. Bone Health: It aids in the absorption of calcium from the intestines and promotes its deposition in bones, contributing to proper bone mineralization and density. Adequate vitamin D levels are important for preventing conditions like osteoporosis, osteomalacia (softening of the bones), and fractures.
2. Calcium and Phosphorus Balance: Calcifediol monohydrate helps regulate calcium and phosphorus levels in the body, which are essential for various physiological processes. It supports the proper functioning of muscles, nerves, and the cardiovascular system.
3. Immune Function: It is involved in the production and function of immune cells, and deficiency in vitamin D has been associated with an increased risk of autoimmune diseases and susceptibility to infections.
4. Mood and Mental Health: Calcifediol Monohydrate has been linked to an increased risk of depression, seasonal affective disorder (SAD), and cognitive decline.
5. Chronic Disease Prevention: Calcifediol Monohydrate has been associated with a reduced risk of certain chronic diseases, including cardiovascular disease, certain cancers (such as colorectal, breast, and prostate cancer), and autoimmune conditions like multiple sclerosis.

Description About Calcifediol Monohydrate
Calcifediol monohydrate, also known as calcidiol monohydrate or 25-hydroxyvitamin D3 monohydrate, is a pharmaceutical form of vitamin D. It is a precursor to the active form of vitamin D, known as calcitriol, which plays a crucial role in regulating calcium and phosphorus metabolism in the body.
When sunlight or ultraviolet B (UVB) radiation hits the skin, a form of cholesterol called 7-dehydrocholesterol is converted into previtamin D3. This compound is then further metabolized in the liver to form calcifediol, which is the main circulating form of vitamin D in the bloodstream. Calcifediol is then converted to calcitriol in the kidneys, which is the active form of vitamin D that binds to vitamin D receptors in various tissues.
Calcifediol monohydrate is used as a pharmaceutical agent to treat or prevent vitamin D deficiency or insufficiency. It may also be prescribed for certain medical conditions that require vitamin D supplementation, such as osteoporosis, osteomalacia, or renal osteodystrophy.