SLU-PP-915
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Place of Origin China
MOQ 1 kg
Package 1kg/Foil bag, 25kgs/Drum (Two plastic-bags inside with Paper-drums), Or as per customer's requirements.
Shelf Life: 2 years under well storage situation
Storage Store in cool & dry place. Keep away from strong light and heat
Payment Term T/T 100% paid in advance
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CAS No.: 2285432-92-8
Molecular Formula: C17H13BFNO3S
Molecular Weight: 341.16
Purity: ≥98.0%
Appearance: White Powder
Function
1. Support Skeletal Muscle Function;
2. Improve cardiac function;
3. Reduce cardiac injury;
4. Reduce fat and improve blood glucose control;
5. Metabolic dysfunction-associated steatohepatitis;
Application
It is used in research concerning mitochondrial function, energy metabolism, exercise mimetics, muscle function, and metabolic diseases.
Description About SLU-PP-915
SLU-PP-915 is a novel pan-estrogen-related receptor (ERR) agonist—an optimized version of SLU-PP-332—designed primarily to enhance cardiometabolic function and exercise endurance.
SLU-PP-915 is capable of simultaneously activating all three subtypes of estrogen-related receptors: ERRα, ERRβ, and ERRγ. These receptors serve as key "switches" regulating cellular energy metabolism, mitochondrial function, and fatty acid oxidation. By activating these receptors, SLU-PP-915 initiates the transcriptional expression of genes associated with exercise adaptation, thereby mimicking some of the physiological effects of exercise.
Studies have shown that SLU-PP-915 improves cardiac function (such as ejection fraction), reduces fibrosis, and increases survival rates in mouse models of pressure overload-induced heart failure. It achieves this by activating metabolic genes, specifically by enhancing fatty acid metabolism and mitochondrial function in the myocardium.
Due to its exercise-mimetic properties, SLU-PP-915 is considered a potential therapeutic candidate for conditions such as obesity, type 2 diabetes, sarcopenia, and muscular dystrophy.
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