Gliclazide

CAS No.: 21187-98-4
Molecular Formula: C15H21N3O3S
Molecular Weight: 323.41
Appearance: White Powder
Purity (HPLC): ≥98.0%

Function
1. Stimulate insulin secretion:
The primary action of gliclazide is to stimulate pancreatic beta cells to secrete insulin; this is the core mechanism by which it lowers blood glucose.
2. Effectively controls blood glucose:
Gliclazide effectively lowers fasting blood glucose, postprandial blood glucose, and glycated hemoglobin (HbA1c), a marker of long-term blood glucose control.
3. Improve insulin resistance:
Enhancing glucose uptake and utilization by tissues such as muscle and adipose tissue, and reducing hepatic glucose production.

Description About Gliclazide
Gliclazide is a second-generation sulfonylurea primarily used for glycemic control in patients with type 2 diabetes. Its mechanism of action involves stimulating insulin secretion from pancreatic beta cells and enhancing peripheral tissue sensitivity to insulin; additionally, it possesses properties that regulate lipid metabolism and inhibit platelet aggregation, making it suitable for managing blood glucose levels in type 2 diabetes patients whose condition is inadequately controlled by diet and exercise.