Citicoline Sodium

Other Name: Citicoline Sodium; CDP-Choline
CAS No.: 33818-15-4
Molecular Formula: C₁₄H₂₅N₄NaO₁₁P₂
Molecular Weight: 510.31
Appearance: White Powder
Purity: 99%

Function
1. Supports synthesis of phosphatidylcholine, a major neuronal membrane phospholipid, aiding membrane repair;
2. Increases levels of acetylcholine and may support dopamine and other neurotransmitters;
3. Enhances mitochondrial function and cellular energy metabolism;
4. Reduces lipid peroxidation and oxidative damage;
may attenuate apoptosis and inflammation;
5. Promotes remyelination and neuronal membrane integrity;
6. Has neuroprotective effects, promotes angiogenesis, and improves brain metabolism;
7. Has an auxiliary restorative effect on cognitive decline such as memory loss and slow thinking;

Description About Citicoline Sodium
Citicoline Sodium is a naturally occurring compound involved in brain phospholipid synthesis and neurotransmitter metabolism.
Several randomized controlled trials and meta‑analyses suggest Citicoline Sodium can improve attention, memory, and global cognitive function in people with vascular cognitive impairment and in some cases of mild cognitive impairment. Effects are generally modest and more consistent for attention and memory than for other domains.
Citicoline Sodium has been studied as an adjunctive therapy after ischemic stroke. Some trials report improved functional recovery and reduced neurological deficits when started early, likely due to membrane repair, reduced free‑radical damage, and support of neurotransmitter systems.
Preclinical studies show neuroprotective effects (reduced cell death, improved mitochondrial function).
Small trials and observational studies indicate Citicoline Sodium may slow cognitive decline in older adults and improve attention and memory performance in age‑related cognitive changes. Evidence is not definitive but suggestive.
Some studies indicate Citicoline Sodium can improve visual function in glaucoma and amblyopia (improved visual acuity, retinal function, and visual field indices), possibly via neuroprotective and neuromodulatory effects on retinal ganglion cells and visual pathways.