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Catestatin

Factory supply Catestatin Peptide Cas 142211-96-9 99% HPLC for healthcare supplement .

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Place of Origin  China
MOQ  1 kg
Payment Term  T/T 100% paid in advance
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Other name: Catestatin Peptide
CAS No: 142211-96-9
Molecular Formula: C107H173N37O26S
Molecular Weight: 2425.84
Appearance: off-white powder
Purity: 99% HPLC
Solubility: Soluble to 1 mg/ml in water
Net Peptide Content: 78% (Remaining weight made up of counterions and residual water)

Biological Activity:
Catestatin is a non-competitive nAChR antagonist; selectively inhibits nicotinic-stimulated catecholamine secretion from chromaffin cells and noradrenergic neurons (IC50 ~ 200 nM). Blocks nicotinic-induced cationic signaling (IC50 ~ 200 - 250 nM) and inhibits nicotinic-agonist induced desensitization of catecholamine release. Also stimulates mast cell release of histamine via a separate mechanism.

Product Process
Catestatin is made using the precise enzymatic hydrolysis control of natural casein in milk, and are made through raw material top treatment, enzymatic hydrolysis, cleaning, concentration, drying, packaging and other processes. The production process is hygienic and safe!

Benefits & Function of Catestatin
1. Improve sleep quality:
Taking Catestatin peptides can help improve sleep quality. Since Catestatin is decomposed, morphine-like active peptides will be produced. This active peptide can help relieve stress. Yes, many people's poor sleep is caused by excessive stress. At this time, it can be improved by taking Catestatin peptide.
2. Improve immunity:
Taking Catestatin can improve immunity, because the active ingredients in Catestatin can also stimulate the proliferation rate of lymphocytes, which can help improve the body's immunity, especially now, many people will have fever when the virus invades. If the situation occurs, then the situation can be improved by taking Catestatin peptide, which can avoid being attacked by viruses and effectively improve the body's immunity.
3. Promote calcium absorption:
Catestatin can also promote calcium absorption. Many people feel that they are constantly supplementing calcium, but they are still deficient in calcium. The fundamental situation is that the supplemented calcium cannot be completely absorbed by the human body, so this can be improved by taking it. In some cases, taking Catestatin can help to promote the speed of calcium absorption, and the effect is also very good, but you need to keep taking it to see the effect.
4. Intestinal regulation function:
Catestatin has the effect of supporting beneficial gut microbes, promoting bifidobacteria and growth and inhibiting Escherichia coli at very low concentrations, significantly reducing the number of Salmonella and effectively preventing diarrhea.
5. Regulate fat metabolism and substance transport:
Hydrolyzed Catestatin can improve the oxidation of low-density lipoprotein by peroxidase and promote the digestion and absorption of high-fat foods. In addition, the close contact between the active peptide component and the surface of small intestinal epithelial cells can change the kinetic constant of leucine across the small intestinal chorionic brush border, and therefore, can effectively regulate and promote intestinal material transport and absorption.

Description About Catestatin
The catestatin peptide is produced from its precursor chromogranin A protein.
Catestatin is a 21 amino acid residue, cationic, hydrophobic peptide. Catestatin is an endogenous peptide that regulates cardiac function and blood pressure. Catestatin is a non-competitive nicotinic antagonist that inhibits catecholamine release through nicotinic acetylcholine receptors (nAChRs).
Catestatin is a new type of short peptide, also known as sleep peptide. As the name suggests, it has the effect of helping to improve sleep quality and has a soothing effect. When Catestatin is hydrolyzed, there will be active peptides like marphine, which is a component that can soothe the mind and reduce stress, and can calm the nerves and improve sleep.
Secondly, Catestatin can regulate human immunity. The decomposed peptides have various physiological functions such as stimulating the proliferation of lymphocytes and resisting infection by external pathogens, so they are very effective in regulating human immunity. Catestatin can also help the immune cells in the body to activate, repair, regenerate, enhance activity, improve the ability of the immune system in the body and the function of autoimmunity, and can also regulate blood pressure and repair brain nerves. It is very suitable for mental factors to cause sleep. Use by people with poor quality.
Finally, Catestatin can promote the absorption of calcium by the human body, because it is rich in casein calcium peptides, casein phosphopeptides, etc. with a high concentration of negative charges, which can form soluble substances with calcium, The body can prevent calcium from forming calcium phosphate precipitation in the neutral or alkaline environment of the small intestine, thereby promoting calcium absorption.

Storage: Store at -20°C

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