Calcifediol

Other Name: 25-Hydroxyvitamin D3; 25-Hydroxycholecalciferol; Calcidiol
CAS No.: 19356-17-3
Molecular Formula: C27H44O2
Molecular Weight: 400.64
Appearance: White to off-white crystalline solid
Purity: 95%~99%

Indications
Treatment of various chronic bone disorders, as well as metabolic bone diseases associated with chronic renal failure, hypocalcemia.

Application
1. In the field of medicine, calcifediol is suitable for the treatment of metabolic bone diseases such as osteoporosis, rickets, and osteomalacia, and is currently the main effective drug for treating osteoporosis in patients with liver insufficiency.
2. In the field of health products, calcifediol has the functions of regulating vitamin D level, promoting the absorption of calcium and phosphorus in the small intestine, improving bone density, and preventing osteoporosis.

Description About Calcifediol
Vitamin D2, vitamin D3, and 1α-hydroxyvitamin D2 currently on the market in my country do not naturally exist in the human body, and calcifediol is an active metabolite of vitamin D3 in the human body.
Calcifediol is a prohormone obtained by hydroxylation of vitamin D3 in the liver. Calcifediol (25-hydroxy Vitamin D3) is the main form of vitamin D in the blood, and it is also an objective indicator of vitamin D deficiency. Compared with conventional vitamin D3, calcifediol has higher absorption efficiency and can improve the vitamin D status in the human body. It is widely used in food, health products, medicine, feed and other fields.
Calcidiol can promote the absorption of Ca2+ and pi in the small intestine, increase the concentration of Ca2+ and pi in serum, reduce the level of alkaline phosphatase and parathyroid hormone in some patients, and reduce the mineral deficiency in some patients. Calcifediol is mainly applicable to the treatment and prevention of metabolic bone disease and kidney disease, hypocalcemia in patients with chronic renal failure undergoing renal dialysis, lack of rickets, various types of male treatment of rickets, senile osteoporosis, Osteoporosis caused by anticonvulsants has a good effect.
Calcifediol itself also has certain activity, and can be used for the treatment of metabolic bone diseases such as osteoporosis, rickets, and osteomalacia, and can also be used for hypocalcemia caused by hemodialysis. Patients with chronic renal failure combined with metabolic bone disease can apply it during dialysis.