Achyranthes Bidentata Polysaccharide

Botanical Source: Achyranthes bidentata
Appearance: Brown Powder
Specification: ≥70.0%
Test Method: HPLC

Function
1. Promotes blood circulation and alleviates dysmenorrhea or amenorrhea caused by blood stasis;
2. Promotes osteoblast differentiation and serves a preventive and therapeutic role in osteoporosis;
3. Regulates glomerular filtration rate and exerts a diuretic effect on edema associated with nephritis;
4. Inhibits chondrocyte apoptosis and promotes cell proliferation;
5. Activates macrophages, enhances phagocytic function, and promotes the proliferation of splenic lymphocytes;
6. Elevates serum hemolysin levels and immunoglobulin content, thereby boosting the body's resistance to disease;
7. Indirectly inhibits tumor growth by modulating the tumor microenvironment and improving blood rheology;
8. Promotes the hepatic synthesis of glycogen from glucose, thereby lowering blood glucose levels;
9. Enhances superoxide dismutase (SOD) activity, reduces serum lipid peroxide levels, and delays cellular senescence;
10. Combats obesity, reduces body weight, and improves insulin resistance;
11. Regulates gut microbiota, improves microbial community structure, and increases the production of short-chain fatty acids (SCFAs);

Description About Achyranthes Bidentata Polysaccharide
Achyranthes bidentata Polysaccharide (ABP) is a class of water-soluble heteropolysaccharides extracted from the roots of the traditional Chinese medicinal herb Achyranthes bidentata. As one of the primary active constituents of Achyranthes bidentata, it is characterized by its low molecular weight, excellent water solubility, and ease of absorption.
Achyranthes bidentata Polysaccharide exhibits a range of biological activities, including immunomodulation (activating macrophages and promoting lymphocyte proliferation), anti-inflammatory effects (inhibiting the NLRP3 inflammasome), antioxidant properties, anti-tumor activity (blocking the metastasis of non-small cell lung cancer by inhibiting the EGFR/EMT pathway), hypoglycemic effects, and anti-aging properties; consequently, it has been developed for use in health supplements and as a candidate for novel drug development.
Achyranthes bidentata Polysaccharide has been shown to significantly enhance the body's immune function, promoting lymphocyte proliferation and NK cell activity, while also boosting serum immunoglobulin levels.