Acetyl Tetrapeptide-5

Sequence: Ac-β-Ala-His-Ser-His-OH
CAS No.: 820959-17-9
Molecular Formula: C20H28N8O7
Molecular Weight: 492.49
Appearance: White Powder
Purity: 98%

Function
1. Improves under-eye bags and puffiness
Inhibits Angiotensin-Converting Enzyme (ACE-1) activity, improves microcirculation and lymphatic drainage around the eyes, reduces vascular permeability, and minimizes fluid retention in local tissues, thereby rapidly eliminating fluid-related under-eye bags.
2. Diminishes dark circles
Improves local blood circulation and reduces vascular-type dark circles caused by blood stagnation and vascular leakage.
3. Anti-glycation and anti-wrinkle effects
Potently inhibits glycation reactions, preventing the cross-linking and hardening of collagen and elastin caused by sugars (formation of AGEs); preserves skin elasticity and suppleness while reducing fine lines and sagging.
4. Enhances skin elasticity
Promotes collagen synthesis and improves the firmness and smoothness of the skin around the eyes.

Description About Acetyl Tetrapeptide-5
Acetyl Tetrapeptide-5 is a synthetic tetrapeptide compound that typically appears as a white, water-soluble powder. It functions primarily by inhibiting collagen glycation, thereby preventing protein cross-linking and enhancing skin elasticity and smoothness. Additionally, it improves vascular circulation around the eyes and relieves vascular pressure, which helps reduce puffiness and edema. Experimental data indicates that its ability to inhibit sebum secretion is comparable to that of retinoic acid, though it is primarily marketed for eye care. In short, it helps minimize eye bags, lighten dark circles, and firm the skin around the eyes.
Acetyl Tetrapeptide-5 is mainly incorporated into eye care products such as eye creams, eye serums, and gels.
Acetyl Tetrapeptide-5 is a high-value cosmetic peptide mainly recognized for improving the appearance of under-eye puffiness, enhancing hydration, supporting firmness, and reducing visible signs of aging. It is especially suitable for premium eye care and anti-aging skincare formulations.